Scientists have found a way to prolong the youth of mice in a laboratory setting by genetically manipulating them to block production of the S6 Kinase protein, which mimics a reduction of calorie intake without actually having to limit the amount of food consumed.
From the article:
“The mice lived longer and were leaner, more active and generally healthier than the control group. We added ‘life to their years’ as well as ‘years to their lives.’”
The genetically altered female mice lived 20 percent longer — living a total of 950 days — or over 160 days more than their normal counterparts.
At age 600 days, the equivalent of middle age in humans, the altered female mice were leaner, had stronger bones, were protected from type 2 diabetes, performed better at motor tasks and demonstrated better senses and cognition, according to the study.
Their T-cells, a key component of the immune system also seemed more “youthful,” the researchers said, which points to a slowing of the declining immunity that usually accompanies aging.
Male mice showed little difference in lifespan although they also demonstrated some of the health benefits, including less resistance to insulin and healthier T-cells. Researchers said reasons for the differences between the two sexes were unclear.
Very interesting research, I’m curious if the ratios for extended youth would also hold true in humans. If so, extended youth: check. Now where’s that brain/internet hookup I’ve been waiting for?
